Promethazine 25mg im - Free E-newsletter
Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family. (IM/IV route preferred).
It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold.
Leukopenia and agranulocytosis have been reported, promethazine 25mg im, usually 25mg promethazine HCl has been used in association with other known marrow-toxic promethazine. Neuroleptic Malignant Syndrome A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome NMS has been reported in association with promethazine HCl alone or in combination promethazine antipsychotic drugs.
Clinical manifestations 25mg NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability irregular pulse or blood pressure, tachycardiadiaphoresis and cardiac dysrhythmias. The diagnostic evaluation of patients with this syndrome is complicated, promethazine 25mg im. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illnesses e.
Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat strokepromethazine 25mg im, drug fever and 25mg central nervous system CNS pathology, promethazine 25mg im. The management of NMS should include 25mg immediate 25mg of promethazine HCl, antipsychotic drugs, if any, and other drugs not essential to concurrent therapy, 2 intensive symptomatic treatment and medical monitoring, and 3 promethazine of any concomitant serious medical problems for which specific treatments are available.
There is no general agreement about promethazine pharmacological treatment regimens come comprare cialis sicuro uncomplicated NMS. Since recurrences of Promethazine have been reported with phenothiazines, the reintroduction of promethazine HCl should be carefully considered. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine HCl in pediatric patients.
In pediatric patients who are acutely ill associated with dehydration, there is an increased susceptibility to dystonias with the use of promethazine HCl, promethazine 25mg im. Other Considerations Administration of promethazine HCl has been associated with reported cholestatic jaundice. Phenergan Promethazine HCl Suppositories should be used cautiously in persons with cardiovascular disease or with impairment of liver function.
Promethazine HCL
Carcinogenesis, Mutagenesis, Impairment Of Fertility Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. Promethazine was nonmutagenic in the Salmonella test system promethazine Ames. Pregnancy Teratogenic Effects Pregnancy Category C Teratogenic effects have not been demonstrated in rat-feeding studies at doses of 25mg. These doses are from approximately 2, promethazine 25mg im.
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Specific studies to test the action of the drug on parturitionlactation, and development of the animal neonate were not done, but a general preliminary 25mg in rats indicated no effect on these parameters, promethazine 25mg im.
Although antihistamines promethazine been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man, promethazine 25mg im. There are no adequate and wellcontrolled studies of Phenergan Promethazine HCl Suppositories in pregnant women.
Phenergan Promethazine HCl Suppositories should be used during pregnancy only if the potential benefit justifies the potential 25mg to the fetus, promethazine 25mg im. Nonteratogenic Effects Phenergan Promethazine HCl Suppositories administered to a pregnant woman within two weeks of delivery promethazine inhibit platelet aggregation in the newborn.
Labor And Delivery Promethazine HCl may be used alone or as an adjunct to narcotic analgesics during labor and delivery.
What Is Phenergan Used To Treat?
Limited data suggest that use of promethazine HCl during labor and delivery does not have an appreciable effect on the duration of labor or delivery and does not increase the risk of need for intervention in the newborn. The effect on later growth and development of the 25mg is unknown.
See also Nonteratogenic Effects. Nursing Mothers It is not known whether promethazine HCl is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Phenergan Promethazine HCl Suppositories, a decision should be promethazine whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Geriatric Use Clinical studies of promethazine formulations did not include sufficient numbers of subjects aged promethazine and over to determine whether they respond differently from younger subjects, promethazine 25mg im.
Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, promethazine 25mg im, dose selection for an elderly patient promethazine be cautious, promethazine 25mg im, usually starting at the low end of 25mg dosing range, reflecting the greater 25mg of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.
Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of Phenergan Promethazine HCl Suppositories pms lorazepam 2mg observed closely.